Alexandra Joyce P. Alvarez, Bryan G. Diano, Matthew Dwayne P. Magbanua (February 2008)
Philippine Science High School Western Visayas Campus – Department of Science and Technology (DOST-PSHS WVC), Brgy. Bito-on, Jaro, Iloilo City 5000, Philippines
ABSTRACT
Jatropha curcas is widely used in ethnomedicine, Studies revealed a wide range of bioactivity including antitumor, anti-inflammatory, anti-parasitic, molluscicidal, insecticidal and haemostatic activities. Anticoagulating activity was also reported on its family member, Jatropha gossypifolia.
Aqueous extracts from the barks, leaves, and roots of Jatropha curcas were subjected to coagulation, hemolysis, and agglutination tests on human blood.
Results showed that bark extracts promoted 100% coagulation. However, leaf and root extracts did not show coagulation. Agglutination test exhibited 100% clumping for the bark and leaf extracts after 5 minutes. The hemolysis test showed that leaf extracts promoted 67% hemolysis, while 7% was observed in the root extracts after 10 minutes.
One-Way Analysis of Variance and Fisher’s Least Significant Difference Test showed greatest clotting and hemolysis in the bark extracts, and greatest agglutination in the leaf and bark extracts.