THE ANTIHYPERGLYCEMIC RESPONSES OF DOMESTIC WHITE MICE (Mus musculus) TO INDUCED HYPERGLYCEMIA AFTER FEEDING ON KAMOTE (Ipomoea batatas) TOPS, KANG KONG (Ipomoea aquatica) LEAVES AND BANANA (Musa sapientum) FLOWERS ENRICHED NOODLES

KIMBERLY C. ABAD, AARON J. ARCIAGA, ADRIAN B. ATAS, HILDA LUZELLE S. MEDRANO (FEBRUARY 2007)

Philippine Science High School Western Visayas Campus – Department of Science and Technology (DOST-PSHS WVC), Brgy. Bito-on, Jaro, Iloilo City 5000, Philippines

ABSTRACT

Noodles, a common food in Asia, are sometimes classified as “junk food” due to high salt, fat, and carbohydrate content and low-quality protein. Vegetable enrichment is a way to make them nutritious. Hyperglycemia means high glucose in blood. Nutritionists promote the use of plants with known antihyperglycemic property in managing such diseases as diabetes.

This study determined the effect of a two-week diet of kamote tops, kangkong leaves, and ABSTRACT banana flowers enriched noodles on the blood sugar level of domestic white mice 30, 60, 90, 120, and 180 minutes after hyperglycemia induction. The relationship between the mean changes of the blood glucose level of mice in each diet and time after hyperglycemia induction was determined and expressed as a mathematical equation using Curve Estimation.

Results showed that the blood glucose of mice fed with kangkong leaves enriched noodles consistently decreased at every testing interval (-7 to -49 milligrams/deciliter) The blood glucose level of mice fed with kamote tops and banana flowers enriched noodles showed a fluctuating trend (decrease in some intervals, increase in some).

The estimated curves for the diets are cubic. The curve for kangkong leaves enriched noodles showed a consistent decline throughout the testing period. The curves for kamote tops and banana flowers enriched noodles showed the same trend: a short decline period, followed by a longer increase period, then followed by a decline around 150 minutes after hyperglycemic induction.

Mice fed with kamote tops, kangkong leaves, and banana flowers enriched noodles exhibited antihyperglycemic responses to induced hyperglycemia.

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