John Rich N. Barrientos, Nathaly Kate N. Bohulano, Karra Alexandria S. Casañares (March 2014)
Philippine Science High School Western Visayas Campus – Department of Science and Technology (DOST-PSHS WVC), Brgy. Bito-on, Jaro, Iloilo City 5000, Philippines
ABSTRACT
This study aimed to develop an antifungal powder against the fungi Trichophyton mentagrophytes using Lantana camera powdered leaves. The L.camara leaves were dried then blended until powder. Food poison method was used to determine the zones of growth of the different concentrations (0%, 40%, 60%, and 100%) of L.camara powdered leaves with L.camara powder to cornstarch ratio. The L.camara powder was evaluated by its particle size, pH and flowability. Results showed that the 100% L.camara powder has the highest antifungal activity against the fungi with the mean diameter of the zone of growth of 3.32±0.164 cm. The Turkey’s Pairwise test and ONE-WAY ANOVA showed that the 100% L.camara powder showed no significant difference on the antifungal activity of the commercial antifungal powder (Clotrimazole) and the 40% and 60% L.camara powder but it showed a significant difference on the 0% L.camara powder. This means that the 100% L.camara powder is the most effective against the T.mentagrophytes and it can be a substitute the commercial antifungal powder (Clotrimazole). The powder particle size range is from ≤0.297 mm, the pH is 6.5 and the angle of repose of the powder for its flowability is 36.9°. The developed. L.camara powder is considered a good powder. It is recommended that the powder be evaluated for its permeability and compressibility.