Rubie Anne G. Bito-on, Ivy Gay A. Gensaya, Paola Bianca F. Jamolin (March 2005)
Philippine Science High School Western Visayas Campus – Department of Science and Technology (DOST-PSHS WVC), Brgy. Bito-on, Jaro, Iloilo City 5000, Philippines
ABSTRACT
This study screened for the antimitotic effect of holothurin extracted from sea cucumber (Bohadschia argus) by comparing the means of the mitotic indices of the onion roots after treatment of the said extract at (a) 1-hour, (b) 3-hour, and (c) 5-hour duration. The existence of any significant difference among the means of the mitotic indices was also determined.
The results of this study showed that there was a marked change in the means of the mitotic index of the onion root tips exposed at different time durations. This showed that the onion root tips responded to the presence of holothurin. There was also a point when the statistical means were not consistent with the antimitotic effect of holothurin, which was established by researchers working on sea cucumbers. The inconsistency occurred when a mean of the mitotic index increased. There was also no significant difference in the mitotic index of the onion root tips.
Having produced inconsistent data, the researchers admit inevitable errors committed in the course of this research. Please refer to the recommendations for future references and baseline of future researches regarding the antimitotic effect of holothurin extracted from sea cucumbers.